Stress related · · · crescentus

项目来源

美国卫生和人类服务部基金(HHS)

项目主持人

REDDY, MICHAEL ·

项目受资助机构

UNIVERSITY OF · ·

立项年度

2015

立项时间

未公开

项目编号

3R01GM111706-01S1

研究期限

未知 / 未知

项目级别

国家级

受资助金额

35628.00美元

学科

GENETICS

学科代码

未公开

基金类别

Non-SBIR/STTR RPGs

关键词

未公开

参与者

CHIEN, PETER ·

参与机构

NATIONAL INSTITUTE · · · SCIENCES

项目标书摘要:DESCRIPTION (provided · · · use energy · · · respond to · · · proteases serve · · · destroying aberrant, · · · proteins and · · · signals through · · · factors. Cells · · · in response · · · how regulated · · · cell cycle · · · is currently · · · proposal addresses · · · proteases target · · · a combination · · · and proteomic · · · on proteases · · · from the · · · crescentus. Aims · · · determine how · · · during proteotoxic · · · the Lon · · · the replication · · · cause growth · · · Aims 3 · · · on how · · · the clamp · · · by the · · · critical for · · · during DNA · · · proteases and · · · highly conserved · · · these results · · · general understanding · · · and stress · · · role of · · · bacterial virulence · · · with the · · · these proteases · · · responses, suggests · · · excellent targets · · · new antibiotic · · · of immediate · · ·

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  • 1.Re···at···Pr···ol···s ···Ba···ri·

    • 关键词:
    • ATP-DEPENDENT PROTEASES; SPECIFICITY-ENHANCING FACTOR; CELL-CYCLE PROGRESSION; AAA PLUS PROTEASE; ESCHERICHIA-COLI; LON PROTEASE; INORGANIC POLYPHOSPHATE; DNA-BINDING; RNA-POLYMERASE; DEGRADATION
    • Ma···ud···am···A.···ie···Pe···
    • 《AN···L ···IE···F ···CH···ST··· V···87》
    • 2018年
    • 会议

    Re···at···pr···ol···s ···a ···al···oc··· t··· a···ct···ll···vi···th···s.···ct···a ··· e···gy···pe···nt···A+···ot···es··· p···r ···ra···io···f ···fo···d ··· n···ve···gu···or···ro···ns···iv···th···pr···ol···s ···an···re···si··· e···t,···ec···ci···an···el···iv··· i···eg···in···ub···at···ar···ey···pe···ic··· i···ft···au···nt···th···gh···e ··· o···da···rs···at···di···th···nh···nt···ec···ci···of···e ···te···ti···ac···er···Re···at···pr···in···gr···ti···is···tr···te···li···d ···qu···ty···nt···, ···l-···le···og···si··· a···ph···ol···ca···ra···ti···. ···th···re···w,··· h···li··· r···nt···rk···at···s ···d ···ht··· o···un···st···in···f ···ul···d ···te···si···n ···te···. ···di···ss···e ···e ···+ ···te···s ···y ···in···al···ed···ow···as···ll··· h···th··· p···ea··· a···de···ye···ur··· c···ge···n ···wt···We···es··· e···pl···of···w ···te··· s···ct···ty···n ···co···ol··· i···nc···si···y ···pl···wa··· F···ll···we···sc···e ··· c···li···a ···e ···og···io···et···in··· t···ne··· m··· m···fy··· a···ts··· a···ne··· t···e ··· r···la··· p···ei···eg···at···.

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