Investigation of the role of carbohydrates from red algae on activation and regulation of innate immunity factors

项目来源

俄(略)学(略)R(略)

项目主持人

S(略)l(略) (略)t(略)n(略)

项目受资助机构

G(略)E(略)k(略)P(略)f(略)I(略)i(略)e(略) (略)o(略)n(略)C(略)i(略)y(略)r(略)s(略)n(略)a(略),(略)s(略) (略)d(略) (略)S(略)n(略)

项目编号

2(略)4(略)0(略)

立项年度

2(略)

立项时间

未(略)

研究期限

未(略) (略)

项目级别

国(略)

受资助金额

0(略)卢(略)

学科

未(略)

学科代码

未(略)

基金类别

未(略)

关键词

s(略)a(略) (略)y(略)c(略)i(略) (略)e(略)l(略) (略)n(略)e(略)m(略)t(略) (略)p(略)e(略);(略)o(略)n(略)s(略)e(略)s(略) (略)l(略)s(略)n(略)y(略)s

参与者

未(略)

参与机构

未(略)

项目标书摘要:nn(略)lement is(略)part of i(略)ity, whic(略)now, serv(略)irst line(略) against (略)ls and al(略)cells. At(略), complem(略)rgoing a (略) in moder(略)y. The ro(略)ement is (略)e detecti(略)g and eli(略) microbia(略) with alm(略) reactivi(略)o with su(略)ecificity(略)amage to (略)lls. Both(略)e and exc(略)lement st(略)re associ(略)ncreased (略)ity to in(略) non-infe(略)ases, inc(略)immune di(略)ronic inf(略)thromboti(略)opathy, t(略)ejection (略)y. It is (略)g that, a(略)of the re(略)ed noncan(略)vation of(略) by coagu(略)brinolyti(略)nzymes, a(略)ns are th(略)uct of en(略)alysis. A(略)ns mediat(略)s, inflam(略)the forma(略)otoxic ox(略)ls, also (略)h muscle (略), the rel(略)tamine fr(略)ls and in(略)cular per(略)The liste(略)s of thes(略) thus hav(略)ced pro-i(略) effect a(略)re, are t(略)f many an(略)tory drug(略) of compl(略)ators, su(略)r H and p(略)interact (略)ydrate mo(略)imarily g(略)lycans an(略)id, on th(略) of the h(略)hogen cel(略)ct the co(略) compleme(略) by stimu(略)binding o(略)t activat(略)bitors. S(略)ysacchari(略) of the p(略)ndidates (略)ng the st(略)glycosami(略)and hence(略) compleme(略)osed proj(略)ore, is a(略)ving the (略)modulatin(略)e system (略)n body us(略) sulfated(略)rides fro(略). The mai(略)he projec(略)eal the g(略)ycan-mimi(略)rties of (略)lysacchar(略) compleme(略)cascade s(略)etter und(略) role of (略)lactans i(略)ement sys(略)ntributio(略)ns from o(略)n cascade(略)ple, fibr(略)ill also (略)to accoun(略)to establ(略)hanism of(略) expand t(略)l spectru(略)ation of (略)accharide(略)ect to an(略)s.The sci(略)elty of t(略)is determ(略) choice o(略)s and bio(略)udies nec(略)evelop an(略)the effec(略) new tool(略)ating and(略)iting bot(略)ity of th(略) pathways(略)ent activ(略) more in-(略)n. The la(略)e oriente(略)ns of oth(略)lement ca(略)e complem(略)ing actio(略)nized onl(略)The innov(略)f the pro(略)aches and(略)r the stu(略)ement act(略)e presenc(略)ed polysa(略)f red alg(略) in using(略)sis model(略)riments c(略) the surf(略)oplates c(略)specific (略)that act (略) and with(略)el of sen(略)n additio(略)iment wil(略)ted for t(略)me on the(略)t of prot(略) incomple(略)(coagulat(略)nolytic),(略) regulato(略)of the co(略)stem. The(略)gained as(略)f the pro(略)pen up th(略)of a new (略)olymers w(略)e structu(略)the marin(略)d habitat(略)for the p(略)nd develo(略)flammator(略) of the b(略)are based(略)ct functi(略)e complem(略)        T(略)nt system(略)ctive fir(略)defense a(略)invasion (略)ic microo(略)he violat(略)delicate (略)which in (略)ing or co(略)roteins i(略)gly assoc(略)the patho(略)eases. Th(略)xpected f(略)lementati(略)project w(略)e possibl(略) of using(略)rides of (略)gin for t(略)on of com(略)orders by(略) the prop(略)lycosamin(略) cell mem(略)ce the pr(略)he comple(略) are synt(略)all human(略) tissues,(略)um of the(略)se of the(略)bstances (略)hthalmolo(略)logy and (略) the gast(略)l tract. (略)ee of the(略)s, algae (略)ides are (略) used by (略)reby reve(略)otential (略)e substan(略)cal pract(略)moment, t(略)terature (略)ly partia(略)on about (略) of these(略) to modul(略)ent and t(略)formed on(略) hemolysi(略)ot to men(略)mplete la(略)on their (略)egulatory(略) compleme(略)th and ve(略)f the pro(略)ct (for e(略)onical an(略)ical acti(略)s) will a(略)rehensive(略)he abilit(略)ed polysa(略)o modulat(略) of compl(略) (complem(略)ion and, (略) regulati(略)actor).  (略)ation of (略) obtained(略)e researc(略) here pre(略)on the ef(略)actans of(略) carragee(略)-, κ-, κ/(略)-types), (略) compleme(略)ctivation(略)human ser(略)eriments (略)on well s(略)ted with (略)agents fo(略)nitiating(略) componen(略)C4. The s(略)actans in(略)binding t(略)accharide(略)t depende(略)sulfation(略)polysacch(略)fation de(略)so import(略)ageenans’(略)o reduce (略)to mannan(略)C4 bindin(略)dies was (略)y activat(略)geenans, (略)with 3,6-(略)ctose. Th(略)arrageena(略)e to bloc(略)inding ce(略)tal serum(略)th more i(略)an non-ge(略)tructural(略)stics mat(略)elioratin(略)ge by pla(略)rinsic pr(略)lement ac(略)ut λ/μ/ν-(略)rrageenan(略)mpletely (略)5 cleavag(略)lactans p(略) in cell (略)logy by i(略)rface gly(略)ibition o(略)g and man(略)g lectin,(略)the class(略)y these s(略)timulated(略), probabl(略)eir struc(略)on carrab(略)f publica(略)://doi.or(略)17_2(略)_(略)https://w(略)irect.com(略)ticle/abs(略)617203142(略)en=7YUmWc(略)QhCNCqM4q(略)XSn-BCsyW(略)SmRcoB5Gz(略)D7lqGXtE2(略)

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