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Initiative for Maximizing Student Diversity in the Biomedical Sciences (IMSD)

项目来源

美国卫生和人类服务部基金(HHS)

项目主持人

JANES, DANIEL E

项目受资助机构

UNIVERSITY OF MISSOURI-COLUMBIA

项目编号

2R25GM056901-13

立项年度

2012

立项时间

未公开

研究期限

未知 / 未知

项目级别

国家级

受资助金额

624187.00美元

学科

未公开

学科代码

未公开

基金类别

Other Research Related

关键词

未公开

参与者

HANNINK, MARK

参与机构

NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

项目标书摘要：DESCRIPTION (provided by applicant): A diverse and well-trained scientific workforce is necessary to advance biomedical research, improve human health and to develop effective remedies for disease. The University of Missouri-Columbia (MU) is the only four-year comprehensive public university in the State of Missouri and has a critical role in training the next generation of scientists. As part of the University of Missouri-Columbia (MU) commitment to scientific training and diversity, and with prior funding from NIH, we have developed a successful and innovative program to prepare underrepresented minority students for biomedical research. We have three objectives for our Initiative to Maximize Student Diversity (IMSD) program. First, to further develop a supportive and engaged peer community of minority undergraduate students that are interested in exploring biomedical research. We will increase the number of MU freshmen/sophomore students who are exploring a career in biomedical research. Second, we will expand a program targeted at MU junior/senior students that involves these advanced undergraduates in independent research experiences and prepares them for graduate study in the biomedical sciences. Third, we will provide a structured and mentored research environment for minority graduate students to develop into independent scientists as they pursue their PhD degree in a biomedical discipline. Further development of our IMSD program will have a substantial impact on diversity at the University and on our nation's scientific workforce. PUBLIC HEALTH RELEVANCE: A robust biomedical research enterprise is required to improve human health and reduce morbidity and mortality from disease. A diverse scientific workforce, which utilizes the talents and skills of all individuals, is a necessary component of a robust research enterprise. The goal of our program is to increase the diversity of PhD scientists trained in biomedical research.

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  • 1.NeverWalk Alone:Clathrin-Coated Vesicle(CCV)Components in Plant Immunity

    • 关键词：
    • GOLGI NETWORK/EARLY ENDOSOME; MEDIATED ENDOCYTOSIS; SALICYLIC-ACID; RECEPTOR FLS2; SUBCELLULAR TRAFFICKING; MEMBRANE MICRODOMAINS; DEPENDENT TRAFFICKING; PATHOGEN EFFECTORS; TRIGGERED IMMUNITY; SECRETORY PATHWAY
    • Ekanayake, Gayani;LaMontagne, Erica D.;Heese, Antje
    • 《ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 57, 2019》
    • 2019年
    • 会议

    At the host-pathogen interface, the protein composition of the plasma membrane (PM) has important implications for how a plant cell perceives and responds to invading microbial pathogens. A plant's ability to modulate its PM composition is critical for regulating the strength, duration, and integration of immune responses. One mechanism by which plant cells reprogram their cell surface is vesicular trafficking, including secretion and endocytosis. These trafficking processes add or remove cargo proteins (such as pattern-recognition receptors, transporters, and other proteins with immune functions) to or from the PM via small, membrane-bound vesicles. Clathrin-coated vesicles (CCVs) that form at the PM and trans-Golgi network/early endosomes have emerged as the prominent vesicle type in the regulation of plant immune responses. In this review, we discuss the roles of the CCV core, adaptors, and accessory components in plant defense signaling and immunity against various microbial pathogens.

    ...

  • 2.The effect of congenic myostatin inhibition on a mouse model of osteogenesis imperfecta (OI) type I/IV

    • Aguillard, Ashley Michelle;Gremminger, Victoria L.;Daghlas, Salah A.;Jeong, Youngjae;Lenz, Kristin L.;Phillips, Charlotte L.
    • 《Annual Meeting of Amer-Assoc-of-Anatomists , Amer-Physiol-Soc, Amer-Soc-for-Biochemistry-and-Mol-Biol ,Amer-Soc-for-Investigat-Pathol ,Amer-Soc-for-Pharmacol-and-Experimental-Therapeut onExperimental Biology 》
    • 2018年
    • APR 21-25, 2018
    • Amer Assoc Anatomists, San Diego, CA
    • 会议
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