STRUCTURE AND FUNCTION OF ANIMAL CELL DNA POLYMERASE @

项目来源

美(略)和(略)务(略)((略))

项目主持人

未(略)

项目受资助机构

U(略) (略)M(略)A(略)S(略)S(略)D(略)H(略)R(略)T(略)

项目编号

2(略)G(略)8(略)-(略)

立项年度

1(略)

立项时间

未(略)

研究期限

未(略) (略)

项目级别

国(略)

受资助金额

0(略)美(略)

学科

未(略)

学科代码

未(略)

基金类别

未(略)

关键词

未(略)

参与者

B(略)N(略)E(略)C(略)I(略)

参与机构

N(略)O(略) (略)T(略)T(略)F(略)N(略)L(略)D(略)L(略)I(略)E(略)

项目标书摘要:Th(略)e objecti(略) project (略)acterize (略) properti(略)eplicatio(略)mammalian(略)rase alph(略)a) and it(略)l gene an(略)n within (略) sites an(略)isms whic(略)ploited t(略)ovel phar(略)gents wit(略) and usef(略)liferativ(略)pecific a(略)roject pr(略)approache(略)oits DNA (略) related (略)to isolat(略) the natu(略)ene(s) sp(略)l alpha. (略)nvolves t(略)rization (略)cture and(略)f the enz(略)novel pol(略)ctive, ac(略)irected p(略)otide inh(略)es develo(略) laborato(略)pproaches(略) into the(略)specific (略). To clon(略)s) encodi(略)lytic cor(略)pol alpha(略)lyze thei(略)tructure (略)iption. A(略)nclude (a(略)ation and(略)of cloned(略)specific (略)ces; (b) (略)n of the (略)ences to (略) characte(略)pha-speci(略)enomic se(略) its/thei(略)tion; and(略)ts to pro(略)ength pol(略)ific cDNA(略)for use i(略)ion of po(略)ression v(略) II. To c(略)racteriza(略) molecula(略)the inhib(略)n and the(略)specifici(略)utylpheny(略)Ps. The g(略)oach will(略) detail h(略)ents work(略)aneously (略)m as spec(略) to disce(略)tal prope(略)e active (略) where th(略)o act. Th(略)approache(略)he use of(略)dures to (略)ffects of(略)forms on (略)interacti(略)adiolabel(略)ves; (iii(略)ble cross(略)ents deve(略)m II, bel(略)) physica(略)ional ana(略)e inhibit(略) binding (略)m III. To(略)evelopmen(略)l alpha-s(略)ive site-(略)tylphenyl(略) analogs (略)ular subs(略)ivatives (略)ol alpha-(略)rker mole(略)s ligands(略)ation in (略)sed ident(略)nd select(略)ation of (略)

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