Bio-MicroElectroMechanical Systems · · ·

项目来源

美国卫生和人类服务部基金(HHS)

项目主持人

RAMPULLA, DAVID

项目受资助机构

MASSACHUSETTS GENERAL ·

立项年度

2018

立项时间

未公开

项目编号

5P41EB002503-15

研究期限

未知 / 未知

项目级别

国家级

受资助金额

1285795.00美元

学科

Bioengineering; Biotechnology; · · · (total) Accidents/Adverse · · · Trauma - · · · Injury - · · ·

学科代码

未公开

基金类别

RESEARCH CENTERS

关键词

未公开

参与者

TONER, MEHMET ·

参与机构

NATIONAL INSTITUTE · · · AND BIOENGINEERING

项目标书摘要:DESCRIPTION (provided · · · mission for · · · Resource Center · · · bridge between · · · and biomedical · · · powerful microtechnologies · · · clinical investigators. · · · the focus · · · research was · · · of microfluidic · · · sorting, especially · · · blood into · · · as well · · · of living · · · In 2008, · · · to expand · · · to include · · · tremendous clinical · · · complex dynamic · · · we look · · · five years, · · · positioned to · · · field because · · · core research · · · fundamentals of · · · the field · · · studies, translation · · · platform technologies, · · · To this · · · our efforts · · · Technology Research · · · Projects. In · · · we will · · · technologies for · · · rare cells · · · other bodily · · · Project 2, · · · a point-of-care · · · enrichment of · · · for early · · · In TR&D · · · will establish · · · containing a · · · and a · · · connected by · · · Project 4, · · · microfabricated devices · · · to examine · · · epilepsy and · · · Our TR&D · · · more than · · · and service · · · into our · · · The training · · · training, laboratory · · · and didactic · · · activities are · · · outreach to · · · publications, web · · · meetings, and · · · BMRC has · · · in developing · · · the interface · · · biomedicine, and · · · the biomedical ·

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  • 1.DN···yp···th···ti···si···ce···nt···um···im···e ···es··· e···y ···st··· c···er···d ···s

    • 关键词:
    • CPG ISLAND HYPERMETHYLATION; RNA-SEQ; BASAL-CELLS; NKT CELLS;METHYLATION; PROGRESSION; EXPRESSION; ADENOCARCINOMA; QUANTIFICATION;ASSOCIATION
    • Gu···Ho···ha···ui···, ···nn···.;···tn··· B···S.···ch···a,···il···.;···, ···Li···Ma···an···ao···in···am··· A···h ···Ru···ll···un··· C···ee···, ···tt··· A···le···w,···le···.;··· C···-L···Gn···e,···dr···;M···sn··· A···an···;E···at···u,···so···.;···, ···ha···J.···ne···Me···t;···ee···ar··· J···aw···ce···ic···l ···Mi···ot···Da··· T···ah···ar··· S···ma···Ha···, ···ie···.
    • 《CE··》
    • 2023年
    • 186卷
    • 13期
    • 期刊

    Ca···r ···ch···ct···ze···y ···om···yl···on···so···te···il···in···f ···ge···ro···in···ma···, ···se···nt···bu···n ···tu···ig···si···s ···er···n.···ro··· h···-r···lu···n ···om···id···in···-c··· D···me···la···n ···ue···ng···e ···nt··· 4···or···om···s ···t ··· u···or··· h···me···la··· f··· t···ea···es···et···ab···st···s ···pr···at···al···an···th···gh···ta···ti···ir···at··· t···r ···ls···TC··· N···ed···on···he···re···ss··· d···in···re···al··· l··· w··· p···er··· m···yl···on···at···ca···si···ci···an···re···ri···d ··· c··· p···if···ti···ge···. ···ns···pt···al···si···ce···en···wi···n ··· c··· h···me···la··· d···in···re···-r···ed···r ···un···el···d ···es···ro···en···mo···th··· i··· s···le···ne···us··· h···or··· a···fi···CD···en···th···pr···nt···pi···nt···ns··· N···ce··· a···fo···IF···-r···te···nt···er···in···ib···ge··· i···ic···d ···in···e ···un···. ··· r···xp···si···of···1 ···IF··· m···ne···th···gs··· i···no···mp···nt···ce···ro···te···um···ge···is···cc···an··· b···he···ti···io···f ···i-···or···mu···y.···us···ar···ep···ne··· c···ge···ay···ap···um···ge···is···ar···in···o-···at···ge··· w···in···fi··· c···mo···al···ci···yp···th···ti···do···ns···e ···ec···le··· b···d ···ci···s ···ic··· f···CT···

    ...
  • 2.Do···eg···ti···of···AP···n ···an··· p···ot···re···ta··· t···mm··· c···kp···t ···ck···

    • 关键词:
    • BREAST-TUMOR CELLS; RNA-SEQ; ACQUIRED-RESISTANCE; PD-1 BLOCKADE;EXPRESSION; GENE; METHYLATION; IPILIMUMAB; SIGNATURES; SUBSETS
    • Fo···Do···as···;E···gh···Ri···rd···;H···, ···;R···el···Hu···r ···Gu···Ho···ha···aS···e,···om···J.···tt···, ··· S···ou···Ni···as···il··· J···na···;T···r,···hm···Ha···en···ir···la··· G···vi··· M···en···eb···am···.;···li···, ···n ···Ma···wa···, ···am···;H···r,···ni···A.
    • 《NP···RE···IO···NC···GY》
    • 2023年
    • 7卷
    • 1期
    • 期刊

    Im···e ···ck···nt···oc···e ···B)···s ···on···at···ef···ac···n ···ie··· w··· m···no··· b···ma···ex···it···or···sp···es···si···si···e ···l ··· s···en···g ···me···om···at···t-···iv···ci···la···g ···or···ll···CT··· a···fu···io··· c···ac···iz···on···in···ou···me···om···od···, ···sh···th···th···EA···NR···pa···ay···du···es···ns···vi···to···B,···de···de···y ···tu···ig···si···Th···RF···eg···ve···gu···or···EA··· s···s ···ri···c ···ia···n ···ex···ss···, ···di···to···mo···et···ge···ty···d ···cl···l ···is···ce·

    ...
  • 5.An···io···-c···oa···ac···ts···ha··· n···ro···l ···ar···e ···St···yl···cc···au···s

    • Pa···,J···if···A ···ai···de···ul···;E···tt···li···os···li···Xe···;F···he···le···;F···in···eu···Ry···Lo···,S···ha···;T···,A···We···,S···ri···;S···tt···el···al···;L···ch···Gr···m ···in···en···e ···en···ri···Da···l;···eg···to···;C···e,··· J·
    • 《Na···om···》
    • 2021年
    • 12卷
    • 1期
    • 期刊
  • 6.NR··· r···la··· e···es···n ···im···ia···ea··· g···s,···pp···si···re···ca···n ···es···n ···ce·

    • 关键词:
    • R-LOOPS; TRANSCRIPTIONAL ACTIVATION; GENOMIC INSTABILITY; CELLSENESCENCE; NUCLEAR; ONCOGENE; PROLIFERATION; RECEPTORS; ALIGNMENT;THREATS
    • Gu···Ho···ha···lc···, ···ri···Wi···er···en···;L···en···he···Ad···Za···ri··· M···us···ba··· T···ni···D.···ng···in···ma···s,···le···ne···rr···is···br···t,···ch··· Y···or···z,···ad···il··· J···na···;H···za···, ···ou···Wi···, ···on···;R···es···ri···ny···;Z···g,···a-···;N···er···fe···Ki···L.···, ···ny···We···y,···nj···n;··· U···;N···an···in···T.···ne···Me···t;···ud···n,···ob···Zo···Le···os···la···y,···ul···he···ra···Sh···al···aw···ce···ic···l ···Ha···r,···ni···A.
    • 《MO···UL···CE··》
    • 2021年
    • 81卷
    • 19期
    • 期刊

    De···ul···on··· o···ge··· s···al···n ···ce···ri···rs···pl···ti···st···s.···me···te···rl···en···(I···) ··· r···dl···nd···an···nt···ex···ss···fo···wi···st···sf···si···ls···on···bu···g ···an···te···te···es···se···er···we···nd···at···e ···ha···uc···r ···ep··· N···1 ···al···s ···os···he···ne···dy···d ···UT···f ···s,···er···t ···ib··· t···sc···ti···l ···ng···on··· R···Po···I,···ne···in···-l···s ··· a···ss···e ···om···n ···ai··· A···e ···li···io···tr··· c···es···me···te···ss···at··· o···R4···an··· b···t ···tr···cr···io···ly···is···IE···xp···si··· E···pi···xp···si···of···4A···nh···es···mo···en···s ···br···t ···ce···el··· w···e ··· d···ti···le··· t···as···e ···om···ma···ns···il··· a···pr···fe···iv···ai···e,···iv···by···re···at···ex···ss··· o···ts···G ···ge···FO···Ap···xi···el···al···f ···as···nd···he···ri···y ···ce···ex···it···ce···bl···hr···ti···om···s ···IE···en···od···, ···si···nt···th···is···re···re···at··· p···wa···Ca···rs···at···ve···ta···d ···s ···ha···m ···ad···in···o ···og···c ···li···io···tr··· m···be···pe···nt··· N···1 ··· t···r ···li···at···.

    ...
  • 7.Ad···ce···ec···lo···s ··· t···pr···rv···on··· m···al··· b···pe···en·

    • 关键词:
    • SUBNORMOTHERMIC MACHINE PERFUSION; MEMBRANE-TRANSPORT-PROPERTIES; DROPLET VITRIFICATION; MICROFLUIDIC DEVICE; HYPOTHERMIC STORAGE; MOUSE EMBRYOS; SURFACE CRYSTALLIZATION; LIVER-TRANSPLANTATION; CLINICAL-APPLICATIONS; DIMETHYL-SULFOXIDE
    • Hu···, ···sh···He···ia···ng···rm···, ···ti···.
    • 《NA···E ···ME···AL···GI···RI··》
    • 2021年
    • 5卷
    • 8期
    • 期刊

    Th···hr···cl···ic···co···te···ol···es···r ··· p···er···io···f ···e ···ma···n ···sp···me···sl···fr···in···vi···fi···io···nd···po···rm···st···ge···mi···he···om···ca···pp···at···s ···bi···ec···ns···n ···s ···ie···we···mm···ze···e ···nc···es···d ···ce···es··· t···e ···ee···ch···og···, ···hl···t ··· t···r ···it···on···re···in···dd···se···ia···e ···bi···io···f ···ro···ri···io···nd···no···ri···io···ma···ia···sc···ce···d ···rm···fl··· e···ne···ng···d ···cu···th···em···in···ha···ng··· T··· R···ew···am···s ···ss···l ···ho···fo···he···es···at··· o···am···ia···io···ci···s ··· t···as···ia··· m···an···s ···cr···nj··· a···di···ss···ho···he···th···' ···li···il··· l···ta···ns···e ···ng···dr···ed·

    ...
  • 8.Th···ip···ni···eg···to···RE··· I···ce···ra···er··· i···ir···at··· M···no···Ce··· a···Su···es··· F···op···is

    • 关键词:
    • TUMOR-CELLS; CANCER-CELLS; OXIDATIVE STRESS; MOLECULAR CHARACTERIZATION;HEPATOCELLULAR-CARCINOMA; COLORECTAL-CANCER; IMPROVED SURVIVAL;LIPID-METABOLISM; GENE-EXPRESSION; PD-1 BLOCKADE
    • Ho··· X···Ro···Wh···e;···li···, ···n ···Wo··· K···h ···K.···tt···, ··· S···uo···on···an···ba··· T···ni···D.···de···ld···, ···he···sl··· B···am···Ho···tz···la···ol···, ···ev···e ···Ma···n,···eu··· L···on···ee···To···Lu···he···e;···et···ra···is···rr···is···re···n,···mu···S.···ri··· L···i;···ho··· K···er···;J···tt···ic···le···;N···an···in···T.···co···, ···;N···, ···er···.;···g,···vi···.;···er···eh···;S···t,···an··· L···et···Ga···ah···ar··· S···ma···Ha···, ···ie···.
    • 《CA···R ···CO···Y》
    • 2021年
    • 11卷
    • 3期
    • 期刊

    Ci···la···g ···or···ll···CT···ar···he···y ···ce···nt···he···oo···re··· w···e ···ia··· s···et···er···es···id···ve···re···to···it···e ···as···is···e ···w ···t ···gl···TC···ro···at···ts···th···la···a ···rd···te···up···ul··· l···ge···is···d ···n ···eo···si···at···ys···he···ar···or···at···wi···bo···in···ns···an···cq···ed···si···nc···o ···F ···ib···rs···ro···cl···l ···tu··· o···RA···ut··· C···. ··· l···ge···is···gu···or···EB···di···tl···nd···s ···ns···pt··· o···he···on···rr··· T···sf···in···F)···ed···ng···tr···ll···r ···n ···ls···ea···ve···yg···sp···es···nd···pi···er···da···n,···er··· c···er···g ···is···ce··· i···ce···of···rr···os··· K···kd··· o···nd···no···TF···pa··· t···r ···ma···n ···me···om···TC···an···he···tu···ig···c ···ec···ar···ar···ll···es···d ···th···ip···il···an···xi···ts···rr···at···1 ··· v···mi···. ···a ···sp···iv···el···ma···ho··· p···en···of···Cs···th···gh···po···ic···d ···n ···ab···c ··· s···at···s ···co···la··· w··· a···rs···li···al···tc···, ···es···ti···of···ea···nt···gi···. ···s,···EB···dr···n ···n ···eo···ti···at···ys···nt···ut···o ···ce···ro···ss···, ···g ···is···ce···nd···ta···si···IG···IC···E:···ro··· s···le···ll···al···s ···pr···ry···d ···tu··· m···no···CT··· w···av···nc···re···nt···si···an··· c··· h···ro···ei···wi···n ···og···c ··· i··· h···os···ic···th···s ···t ···ul···s ···is···ce··· B··· i···bi···s ··· t···er···to··· i···ce··· A···va···n ···th··· p···wa···wi···n ···s ···co···la··· w··· a···rs···li···al···tc···, ···nt··· t···he···eu··· o···rt···ti···

    ...
  • 9.Ne···op··· f···ti···l ···fi···g ··· c···ki···au···nt···on···r ···ie··· w··· m···ip···re···re···in···ti···: ···as···tu··

    • Al···nd··· N···li···.;···ym···av···J.···rm··· J···yl···.;···ri···Pr···il···Vi···, ···m;···ll··· N···li···op··· A···;S···re···Al···on···gh··· Z···a;···ro···Ni···as···oo···iz··· S···y ···I.···ff···eb···a ···Pa···rn···, ···k ···Th···so···Ry···W.···im··· D···el···ns···, ···ha···K.
    • 《JO···AL··· A···RG···ND···IN···L ···UN···GY··· P···TI··》
    • 2021年
    • 9卷
    • 2期
    • 期刊
  • 10.Ev···at··· o···nd···in···es···an···us··· E···ge···yp··· o···ir···at··· t···r ···ls···d ···sm···NA

    • 关键词:
    • METASTATIC BREAST-CANCER; ESTROGEN-RECEPTOR-ALPHA; MUTATIONS; MECHANISM; EXPRESSION; OUTCOMES; THERAPY; CARM1; DRUG
    • Su···re···, ···ak···;D···sh···ar···sh···;Z···g,···ng···Ba···a,···it···Wi···er···en···;A···o,···co···Si···, ···n ···Fo···Do···as···;L···er···Ma···ew···pu···Ra···Ia···te···oh···on··· M···et···he···ra···Sh···al···ab··· D···el···
    • 《BR···T ···CE···ES···CH···D ···AT···T》
    • 2021年
    • 188卷
    • 1期
    • 期刊

    Pu···se···er···ut···ef···ac···f ···mo··· t···ap··· t···ar··· e···og···re···to···ER···os···ve···ea···ca···r ···li···ed··· t···ac···si···n ···li···d-···ep···en···SR···ut···on···wh··· c···er···ea···nt···si···nc···o ···ma···e ···ib···rs···Is···Mo···or··· f···th···me···nc···f ···h ···at···s ··· e···le···di···ua···ed···er···. ···th···as···se···TC···nd···DN···as···de···ti···of···R1···ta···ns···th···e ··· o···va···ti···no···nv···ve···pr···he···or···e ···er···at··· o···nd···in···es···an··· P···en···an···et···s ···a ···sp···iv···oh··· o···5 ···en···th···rm··· r···pt···po···iv···et···at···br···t ···ce···we···ol···d ···cu···in···um···ce··· (···s)···d ···el···d ···ig···en···iv··· m···od···r ··· d···ct··· o···SR···ut···on···n ···se···Cs···n ···ie··· w··· s···ic···t ···sm···or···e ···ul···eo···ex···ct··· o···ir···at··· t···r ··· (···NA···we···rf···ed···pa···le···na···is··· E··· m···ti··· u···g ···ti···x ···pl···di···al···R ···PC···an···xa···ed···e ···ee···t ···we···th··· t···pl···or··· F···ll···we···ol···d ···gl···TC···ro··· s···et··· t···e ···ie··· a···re···we···NA···pr···io···o ···lo···al···na···me···ds··· e···ua···g ···oc···e ···po···ve···s.···su··· H···-s···it···ty···R1···qu···in···ro···TC···ev···ed···no···nd···ig···on···mu···io···in···% ···pa···nt···Th··· w··· c···or···t ···h ···sm···NA···qu···in···n ··· o···as··· E···ge··· o···SR···ut···on···as···rr···te···ot···it···im···o ···as···ic···la··· a···du···io···f ···th···py···ll···ng···ch···cu···nc···Th···re···ce··· a···SR···ut···on···om···ed··· E··· w··· t···, ··· a···ci···d ···h ···ke··· s···te···ro···ss···-F··· S···iv···on···-b···d ···ra···s ···= ···00··· b···un···er···to···he···on···-b···d ···ra···s ···= ···3)···om···ed···th···R1···ta···ca···, ···re···ta···CT···wi···wi···ty···ES···sh···d ···el···te···R-···ct···to···NA···gn···re···on···te···wi···th··· p···ic··· r···on···to···co···li···ho···na···he···ie···Co···us··· B···d-···ed···ri···mo···or··· m···gu··· t···se···ti···of···ec···on···er···ut··· f···wo··· w··· A···es···an···R-···it··· b···st···nc···

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