How partners define Myosin VI function in cells:towards a mechanistic understanding of the cellular roles of Myosin VI-MyoActions
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法(略)科(略)金(略)R(略)
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A(略)1(略)E(略)0(略)
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2(略)
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未(略) (略)
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国(略)
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5(略)1(略)0(略)
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V(略)s(略)é(略) (略)n(略)r(略)
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P(略)e(略)f(略)n(略)
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M(略)m(略)n(略)H(略)U(略)
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U(略)n(略)r(略)y(略) (略)r(略);(略) (略)T(略)T(略)R(略)S(略) (略)R(略)E(略)E(略)2(略)S(略)U(略)U(略)-(略)T(略) (略)H(略)H(略)C(略)N(略)T(略)C(略)E(略)C(略)E(略)C(略)C(略)A(略) (略)D(略)E
项目标书摘要:Su(略)mmary:For(略)on by mol(略)rs powers(略)ellular p(略)tivated b(略)motors ca(略)force for(略)echanisti(略)h as tran(略)ring and (略)ization.H(略)actual ac(略)tor perfo(略)nerating (略)ot been d(略) in situ (略) their ce(略)s.The des(略)domains t(略)the motor(略)dimerizat(略)if the mo(略)ric)great(略)es the co(略)of heads (略)ch of the(略)ng steppi(略)little is(略)t how mot(略) their ac(略) given de(略)e tuning (略)tility pr(略)en less i(略)ut how th(略)t of the (略)rticular (略) contribu(略)ing the a(略)rforms in(略)ctions wi(略) Myosin V(略)nique and(略)otor sinc(略)nical pro(略)ows it to(略)anchor or(略)ctin fila(略)produces (略)e reverse(略)than all (略)ns and ca(略)ted in ce(略)inct tail(略)argoes).I(略)ell-suite(略)eating th(略)l partner(略)pecifying(略) of molec(略).Understa(略)ontrol of(略)vation in(略)ssential (略)ormation (略)ellular f(略)is critic(略)n experim(略)robe the (略)the motor(略)ts own ce(略)ronment,((略)how recru(略)egulated (略)d time an(略)tners dic(略)le of the(略)articular(略)periences(略)rce(load)(略) a multi-(略)sis(from (略)biology,d(略)of specif(略)rs/modula(略)ce genera(略) motility(略) cell bio(略)vide crit(略)ts into h(略)nchor and(略)heir trac(略)their par(略)fy and co(略) actions.(略)genetic a(略)l be deve(略)Partner 2(略)y small m(略)le to inf(略)motor pro(略)generate (略)nchors,or(略)s unable (略)aking adv(略)he prelim(略)recently (略) Partner (略)esigned a(略)udy to ga(略)tic insig(略)e role.My(略) the fiss(略)lar inter(略)om melano(略)cess that(略)d for the(略)on and fu(略)ins have (略)ated in m(略)sion in m(略)nt contex(略) proposed(略) Myo6 wil(略)undamenta(略)hts into (略)act on me(略) MyoActio(略) will res(略)chanistic(略)ing of th(略)ular role(略)tive appr(略)previousl(略)for study(略)ar motors(略)s will ha(略)mplicatio(略)rstanding(略)s associa(略)is motor.(略)ction has(略)iated wit(略)due to th(略)ion of st(略)n the inn(略)larly,mut(略)s adaptor(略)PTN and G(略)sult in d(略)ologies.F(略) has also(略) to contr(略)ncer prog(略) may serv(略)ntial the(略)rget.
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