Privacy preservation poses significant challenges in third-party data sharing, particularly when handling table data containing personal information such as demographic and behavioral records. Synthetic table data generation has emerged as a promising solution to enable data analysis while mitigating privacy risks. While Generative Adversarial Networks (GANs) are widely used for this purpose, they exhibit limitations in modeling table data due to challenges in handling mixed data types (numerical/categorical), non-Gaussian distributions, and imbalanced variables. To address these limitations, this study proposes a novel adversarial learning framework integrating gradient boosting trees for synthesizing table data, called Adversarial Gradient Boosting Decision Tree (AGBDT). Experimental evaluations on several datasets demonstrate that our method outperforms representative baseline models regarding statistical similarity and machine learning utility. Furthermore, we introduce a privacy-aware adaptation of the framework by incorporating k-anonymization constraints, effectively reducing overfitting to source data while maintaining practical usability. The results validate the balance between data utility and privacy preservation achieved by our approach.

Deep generative models, such as generative adversarial networks (GANs), have been employed for de novo molecular generation in drug discovery. Most prior studies have utilized reinforcement learning (RL) algorithms, particularly Monte Carlo tree search (MCTS), to handle the discrete nature of molecular representations in GANs. However, due to the inherent instability in training GANs and RL models, along with the high computational cost associated with MCTS sampling, MCTS RL-based GANs struggle to scale to large chemical databases. To tackle these challenges, this study introduces a novel GAN based on actor-critic RL with instant and global rewards, called InstGAN, to generate molecules at the token-level with multi-property optimization. Furthermore, maximized information entropy is leveraged to alleviate the mode collapse. The experimental results demonstrate that InstGAN outperforms other baselines, achieves comparable performance to state-of-the-art models, and efficiently generates molecules with multi-property optimization. The code is available at: https://github.com/tang777777/InstGAN. © 2025 International Joint Conferences on Artificial Intelligence. All rights reserved.