Dy···gu···io···f ···lu··· r···se···ta···ca···e ···ic···ve··· m···bo··· a···rm···ti···or···mo···en···s.···we···, ···ly···al···th··· a···cu···nt···li···ed···r ···nt···in···ib··· c···en···ti···in···mp··· b···og···l ···pl··· H···, ···ut···ze···e ···hl···pe···ic···co···ti···of···bo···by···bo···bi···ng···ot··· (···) ···de···op···si···e-···te···ri···e ···so···et···ab···vi··· s···it··· N···te···iq···kn··· a···yp···ol···ze···29···ch···ca···xc···ge···tu···io···ra···er···yp···CE···. ···de···st···e ···t ···, ···h ···un···e ···os···in···g ···e ··· f···he···ng···er···to···nd···no···en···es···e ···nt···ti···of···bo···ov···a ···e ···ce···at··· r···e ··· t···M)···ib··· b···in···nd···s ··· R···"c···ed···nf···at···, ···ch···ow···e ···ha··· t··· r··· d···ct···e ···hy···-C···. ···h ···ec···n ···re···ka··· s···if···fo···ib···, ···h ··· m···ma···ac···ou···si···l ···m ···og···us···ga···of···mi··· s··· a···st···tu··· f···ex···le···lu···e ···ri···e-···ho···at···Ri···e ···ce···at··· w···me···re···or···mm···an···ll···sa···an···er··· w···h ··· t···st···te···f ···-m···ib··· i··· H··· c··· l···. ···s ···hl···ts···e ···en···l ··· u···g ···et···ll···nc···d ···ip···mi···in···g ···te··· s··· a···BP··· m···ur···et···li··· i···if···en···io···ic···fl···s,···ss···, ··· p···io···ic···at··· C···ri··· ©···20···er···n ···mi··· S···et··

We···ve···ga···th···ag···ic···so···ce···op···ie···nd···ch···e ···et··· o···ue···mo···ul···in···se···s ···he···o-···et···ic···ps···s,···on···-n···(4···(n···1-··· w···e ··· =···4'···s[···py···in···et···en···mi···-[···'-···he···]-···'-···ul···at···H ···d ···wo··· b···ee···ap···e ···fo···es···d ···ni···iu···at···s ···mo···th···ry···ll···ti···of···on···-n···(4··· T···fo···wi···fo···is···ru···ra···ry···ls···e ···or···: ··· g···t-···e ···ms···C(···)(···(4···o1···e2···6]···te···ot···H(··· (···an···C(···)(···(4···o2···e1···6]···te···ot···H(··· (··· a···tw···e-···d ···l3···ca···la··· f···s,···(N···(3···4)···e)···8)···.8···.2···ce···r ··· 6···2)···3)···d ···NH···3)···)[···Cl···o2···e2···6]···te···ot···H(··· (··· r···ec···el···St···tu··· a···ys···re···l ···t ···in···es···gl···bl···tr···ur···ch···es··· 3···hi···th···ng··· b···ee···ei···or··· p···yl···ou···ex···d ···ca··· d···ee···o ···om···at···he···ch···rg···gu···, ···l3···n ···Th··· g···t-···ap···at···[C···e4···6]···) ···ec···s ···ea···e-··· a···F-···ch···ca···hi···ch···es··· c···-2···nd···0 ··· a···98··· r···ec···el···pe···ub···tu···n ···lo···pi···e-···by···gh···in···-I···Li···is···th···em···at··· d···nd···e ···th···e-··· a···F-···NM···es···nc···in···as···by···1 ··· 0··· p···K,···sp···iv···, ···h ···h ···it···al···ra···ne··· C···I ···te···Th···pt···l ···pe···ur···or···pe···la···ed···p)···-1···ch···ca···xc···ge···tu···io···ra···er···yp···CE··· w··· [···Fe···L6···-)···ps···s ··· f···d ···be···ve···ly···op···io··· t···he···mb···of···-I···en···s,··· w···h ···co···st··· w··· t···Xe···em···l ···ha··· a···le···in···s ··· p···al···xp···. ··· s···em···c ···dy···s ···il···te···y ··· t···bi···y ···th···M4···(4···ca···le···fu···er···gh···ht··· t···e ···al···ga··· s···em···or···ve···in···es···si···se···rs···th···gh···sh···ed···-1···re···an···.

Ge···ic···y ···od···(G···co···as···ge··· d···ct···e ···ma···ti···es···nc···ma···g ···I)···ab···no···nv···ve···su···za···n ···ge···ex···ss··· a···ce···pr···fe···io···t ···tu···y ···im···d ···et···io···ep···. ···ng···pe···la···ed···-1···in···mb···ti···wi···ch···ca···xc···ge···tu···io···ra···er···n ···co···as···pp···ch···ow···s ···er···ST···na···s ···ra···si···e ···te···de···ti···an···io···ec···r ···gi··· G···RI···nt···t ···nt···ev···pe···o ···e ···lu···na···ca···pr···in···ou···as···si···s ···we···as···e ···om···c ···te···l ···te··· T···1 ···a-···ta···e ···a)···d ···to···bi···ng···ot··· (···).··· i···ov···nd···ta···ng··· h···r-···T ··· w··· p···ei··· s···ct···l ··· c···ut···on···st···es···re···rf···ed··· f···he···ha···te···e ··· X···la···te···ti··· X···y ···st···og···hy···li···ed···e ···at··· o··· h···-o···pa··· X···in···g ···e ···di···d ···MD···mu···io··· a···mu···en···s ···er···nt···on···me···hi···e ···e ···th···ri··· o···he···se···d ···T ···tr···. ···uc···al···ud··· a···MD···mu···io···wi···re···se···ti···bl···ut···s ···er···ad···io··· i···gh···eg···in···he···la···ns··· b···ee···oc···pr···in···ru···re···d ···T ···tr···.

Cr···op···e-···ed···os···or···re···om···ng···en···fo···he···tr···ns···ve···te···on··· b···ed···ll···el···nt···rg··· v···Xe···9 ···. ···am···li··· s···te···g ···ea··· t··· c···to···ne···or···at···so···le···gr···te···en···o ···dr··· o···an···te···in···ze···cr···ne···an···fl···es···ce···en···ng···sa···al···ed···an···at··· o···he···gr···ti···st···, ···h ···ti··· c···en···ti··· r···in···ro···00··· t···00···, ···en···g ···th···ry···ph··· s···ie···n ···ut···. ··· a···ti···of···ce···ca···ni···nh···as···CA···ro···n ···ge···o ···en···es···on···de···nc···na···ed···yp···ha···bi···ns···(C··· l···to···B ···ag···ga···n ··· p···uc···th···xp···ed···1 ···-C···om···x.···B ···we···ig··· a···ni···at···8 ···or···e ···op···mi···so···e ···I ···n ··· e···ac···ul···CA··· i···ym···wh··· i··· b···ar··· o···an···. ···ng···pe···ES···MR···e ···lo··· t···ro···of···oi···om···y ···de···ti···th··· t···is···me···Un··· C···at···ti···co···ti···, ···ob···ve···ha···so···e ···I ···du··· a···rg···Xe···9 ··· c···ic···sh··· c···ge···el···= ··· p··· r···ti···to···ee···os···or···ha···AX···(d···a ···.7···m)···hi···in···at···th···tr··· p···nt··· f···is···me···ec···c ···ec···n.···we···, ···ic···me···-d···nd··· c···ic···sh··· d··· i···ca··· t··· b···en··· d···gg···at··· c···ri···es··· t···ob···ve···e-··· N···ch···ca···hi···ch···e ···t ···no···ll···ss···ed··· b···en···-t···et···nd···. ···al··· w···et···in···th···mo···er···cr···op···e ···ut···s ···ro···hy···-C··· s···ra···n ···tr···, ···ch···ab··· u···as···it··· d···ct··· o···io···so···ro···n ···pl···s.···es···ns···ts···to···yp···ha···so···io···eh···or···pp··· f···he···ev···pm··· o···en···bi···ns···, ··· w··· r···ir···ei···rp···at··· o···he···ta···ev···sl···bt···ed···r ···y ···er···lu··· c···to···ne··