Synthesis,Functionalization and Incorporation of Aryl-Mimetics with High sp3 Character in Molecules with Anti-chagasic Activity:A Viability Study of Potential Drug-Likeness Modulators in Bioactive Compounds
项目来源
巴(略)罗(略)金(略)P(略))
项目主持人
L(略) (略)l(略)D(略)
项目受资助机构
I(略)i(略)o(略) (略)m(略).(略)v(略)i(略)e(略)t(略)a(略)e(略)m(略)a(略)a(略)n(略)S(略)r(略)l
立项年度
2(略)
立项时间
未(略)
项目编号
2(略)0(略)-(略)
项目级别
国(略)
研究期限
未(略) (略)
受资助金额
未(略)
学科
P(略)i(略) (略)e(略)s(略)d(略)t(略)a(略)s
学科代码
未(略)
基金类别
S(略)l(略)h(略) (略)B(略)i(略)o(略)r(略)((略)e(略)
关键词
F(略)n(略)m(略)o(略) (略)d(略) (略)m(略) (略)i(略);(略)a(略)a(略)t(略)e(略)r(略)o(略) (略)t(略) (略)â(略)a(略)P(略)u(略) (略)u(略)s(略)B(略)i(略)s(略)d(略) (略)c(略)r(略)d(略)r(略)s(略)B(略)n(略)o(略)D(略)ç(略)e(略)a(略) (略)á(略)c(略);
参与者
J(略) (略)r(略)o(略)i(略)B(略)s(略)t(略)
参与机构
未(略)
项目标书摘要:Ch(略)e is caus(略)arasitic (略)rypanosom(略) is class(略)e World H(略)ization a(略)ed Tropic(略)NTD),affe(略)6 million(略)ecially i(略)rica.Cons(略) low inve(略) major ph(略)l compani(略)the Drugs(略)ted Disea(略)ive(DNDi)(略)ship with(略)d USP,est(略)e collabo(略)ortium LO(略)te Drug D(略)d Develop(略) endemic (略)m this co(略)e chemica(略)939 emerg(略)of molecu(略)gh anti-c(略)ential di(略) DNDi-but(略)timizatio(略)drug-like(略)e similar(略) their AD(略)on,Distri(略)bolism,an(略))properti(略)e of appr(略)In this c(略)present p(略) not only(略)e the dru(略)erties of(略)ted chemi(略)through t(略)sical bio(略)of arenes(略)dines wit(略)character(略)o compare(略)ility of (略) bioisost(略) academic(略) medicina(略) for NTDs(略)es and(he(略)es will b(略)ed,functi(略)d incorpo(略)the molec(略)ld to ass(略)DME and a(略)c propert(略)llel,the (略)ks to dev(略)ler and m(略)synthetic(略)y aimed a(略)zing the (略)pirohepta(略)campaigns(略)
- (略)
