XAI技術を活用した手指巧緻性評価による認知症早期支援システム開発

项目来源

日本学术振兴会基金(JSPS)

项目主持人

林 敦子

项目受资助机构

神戸大学

立项年度

2024

立项时间

未公开

项目编号

24K02765

研究期限

未知 / 未知

项目级别

国家级

受资助金额

17810000.00日元

学科

高齢者看護学および地域看護学関連

学科代码

未公开

基金类别

基盤研究(B)

关键词

手指巧緻性 ; アルツハイマー病 ; 軽度認知障害 ; 高齢者 ; 認知症 ; XAI ; working memory

参与者

グライナー 智恵子;中村匡秀;陳思楠

参与机构

神戸大学,保健学研究科;神戸大学,数理・データサイエンスセンター

项目标书摘要:今年度は、軽度認知症障害、認知症の被験者との比較のために、手指タッピングによる二重課題を健常高齢者に行った。課題間の違いを見出しており、手指運動解析も進めているところであり、順調に進んでいると考える。健常高齢者、SCD、MCI、ADの被験者4群について、手指タッピングによる二重課題を行う。二重課題の難易度を工夫することで被験者4群の相違点を見出し、MCIやADの評価や早期診断・鑑別の可能性を探る。タッピング課題での反応時間、正答率といった行動指標と画像認識による手指の特徴量の両評価を比較して、XAI評価の有用性に関する精度、妥当性について検証することを目的としている。今年度は、健常高齢者を対象に手指運動による介入課題を行い、認知機能と運動機能の変化を検討した。介入課題前後の認知機能と運動機能を比較し、介入課題が両機能とどのように関連しているのかを明らかにし、さらに、手指運動を用いたWorking Memory(以下、WM)課題の有用性について検討した。健常高齢者41名を、手指運動を伴うWM課題を行う群(A群):13名、手指運動を行う群(B群):14名、発声によるWM課題を行う群(C群):14名の3群にランダムに割り当てた。手指運動として、指タッピングを実施した。介入課題の前後にTrail Making Test-A,B(TMT-A,B)、運動機能評価(Purdue Pegboard Test(PPT)を実施した。介入前後比較において、A群では,TMT-AとBの所要時間の有意な短縮から手指運動を伴うWM課題が注意・遂行機能、WMに働きかける可能性が考えられた。B群とC群では、認知機能に有意な変化はみられなかったことより、手指運動を伴うWM課題が認知機能向上に影響する可能性が示唆された。3群間の比較では有意な変化はなく、群間差がみられるほどの介入効果はないと考えられた。PPTでは、WM課題を行ったA群とC群で組み立ての本数が有意に増加した。WM課題によって手と目の協調運動やWMを必要とする組み立て本数が有意に増加した可能性が示唆された。引き続き、手指タッピングによる二重課題を健常被験者のみでなく、SCD、MCI、ADなどの被験者についても実施していけるよう準備をしていく。Reason:今年度は、軽度認知症障害、認知症の被験者との比較のために、手指タッピングによる二重課題を健常高齢者に行った。課題間の違いを見出しており、手指運動解析も進めているところであり、順調に進んでいると考える。Outline of Research at the Start:健常高齢者、主観的認知機能低下、軽度認知機能障害(mild cognitive impairment,以下MCI)、軽症アルツハイマー病(Alzheimer’s disease,以下AD)を対象に手指運動課題を実施し、認知・精神機能との関連から対象者間の横断的な評価を行うとともに長期的な介入効果を明らかにする。手指運動施行時に説明可能なAI(XAI)による手指と顔の認識を行う。健常高齢者からADへ移行する過程において、XAIによる評価を従来の評価と比較・検証し、MCI、ADの新たな鑑別手法の確立を目指す。さらに評価・鑑別で得られた手指巧緻性に関する知見を活かした支援プログラム開発を行う。

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  • 1.Non-Invasive Showering Estimation Utilizing Household-Adaptive Models and Washing Time Data

    • 关键词:
    • dual-proxy framework; shower detection; non-invasive sensing;household-adaptive modeling; proxy feature; proxy-driven scheme; featureselection; Pareto analysis; calibration; smart home;FEATURE-SELECTION
    • Nakata, Takuya;Hashizume, Jiro;Yanada, Akihiro;Nakamura, Masahide
    • 《ELECTRONICS》
    • 2025年
    • 14卷
    • 21期
    • 期刊

    This study introduces a dual-proxy framework for household-adaptive, non-invasive shower detection using standard water-heater logs. The framework leverages proxy at two complementary levels: a feature-level proxy (washing_seconds) that captures washing duration, and a scheme-level proxy (proxy-driven training) that enables learning in periods without direct shower labels. The proxy feature (washing_seconds) serves as an indirect descriptor of washing behavior, enabling effective inference even under label scarcity. We investigated three research questions: (RQ1) the effectiveness of proxy features in improving shower detection, (RQ2) how proxy-driven evaluation identifies compact yet reliable feature subsets, and (RQ3) the robustness of these subsets in long-term, real-world scenarios. Experiments on two households showed that washing_seconds consistently improved discrimination (raising summer PR-AUC, lowering non-summer false alarms), and that compact subsets of only two or three features, anchored by the proxy feature, achieved stable performance across households. The evaluation represents an illustrative example based on two cooperating households, providing practical evidence of the framework's real-world applicability. Evaluation in real-world conditions confirmed robustness: representative subsets maintained micro PR-AUC 0.724-0.728, micro F1 0.66-0.69 (macro F1 0.55-0.58), and summer PR-AUC near 0.87, with generalization gaps within +/- 0.01 for discrimination and small positive shifts for F1 (+0.02-+0.05). These results demonstrate that proxy can function both as a feature and as a methodological principle, and that the proposed framework is model-agnostic and transferable to other learning architectures. It provides a foundation for adaptive, privacy-preserving smart home applications that can scale to broader household and healthcare contexts.

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  • 2.Towards Sensor-Based Mobility Assessment for Older Adults: A Multimodal Framework Integrating PoseNet Gait Dynamics and InBody Composition

    • 关键词:
    • Anthropometry;Correlation methods;Gait analysis;Health risks;Muscle;Quality control;Composition metric;Dynamic gaits;Health monitoring;Intracellular water;Mobility and health correlation;Mobility assessments;Muscle mass;Older adults;Skeletal muscle;Visceral fat
    • Chen, Sinan;Kong, Lingqi;Tong, Zhaozhen;Yamaguchi, Yuko;Nakamura, Masahide
    • 《Sensors》
    • 2025年
    • 25卷
    • 18期
    • 期刊

    The acceleration of global population aging has driven a surge in demand for health monitoring among older adults. However, traditional mobility assessment methods mostly rely on invasive measurements or laboratory-grade equipment, making it difficult to achieve continuous monitoring in daily scenarios. This study investigated the correlation between dynamic gait characteristics and static body metrics to enhance the understanding of elderly mobility and overall health. A sensor-based framework was implemented, which utilizes the Short Physical Performance Battery (SPPB), combined with PoseNet (a vision-based sensor) for dynamic gait analysis, and the InBody bioelectrical impedance device for static body composition assessment. Key variables comprised the dynamic metric mean directional shift and static metrics, including skeletal muscle index (SMI), skeletal muscle mass (SMM), body fat percentage (PBF), visceral fat area (VFA), and intracellular water. Nineteen elderly participants aged 60–89 years underwent assessments; among them, 16 were males (84.21%), and 3 were females (15.79%), 50% were in the 80–89 age group, 95% did not live alone, and 90% were married. Dynamic gait data were analyzed for center displacement and horizontal directional shifts. A Pearson correlation analysis revealed that the mean directional shift positively correlated with SMI ((Formula presented.), (Formula presented.)), SMM ((Formula presented.), (Formula presented.)), and intracellular water ((Formula presented.), (Formula presented.)), highlighting the role of muscle strength in movement adaptability. Conversely, negative correlations were found with PBF ((Formula presented.)) and VFA ((Formula presented.), (Formula presented.)), suggesting that greater fat mass impedes dynamic mobility. This multimodal integration of dynamic movement patterns and static physiological metrics may enhance health monitoring comprehensiveness, particularly for early sarcopenia risk detection. The findings demonstrate the framework’s potential, indicating mean directional shift as a valuable dynamic health indicator. © 2025 by the authors.

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  • 3.Vision-Based Assessment of Skeletal Muscle Decline: Correlating Gait Variance with SPPB Performance

    • 关键词:
    • elderly fall risk; gait analysis computer; vision; short physicalperformance battery; non-invasive assessment;MONITORING-SYSTEM; VALIDITY
    • Tong, Zhaozhen;Chen, Sinan;Yamaguchi, Yuko;Nakamura, Masahide;Yen, Hsin-Yen;Lee, Shu-Chun
    • 《HEALTHCARE》
    • 2025年
    • 13卷
    • 12期
    • 期刊

    Background: With the global population aging, the proportion of the elderly is increasing, leading to health challenges. The decline in the elderly's physical function raises their fall risk, which affects their health and burdens the healthcare system. Traditional fall risk assessment methods like Short Physical Performance Battery (SPPB) have limitations, while computer vision technology shows potential but also has drawbacks. Objective: This study aims to use computer vision technology to quantify the elderly's gait movement features, analyze their correlations with SPPB test scores and duration consumption, and explore a solution for long-term monitoring and more efficient fall risk assessment. Methods: Data from 19 elderly Japanese subjects, including SPPB test data and camera-captured body movement data, were analyzed. Python (Version 3.12.6) was used to obtain JSON data, calculate movement distances, and construct a comprehensive index. Correlation analysis and principal component analysis (PCA) were performed. Results: The variance mean indicator of the comprehensive index associated with movement distance had a significant negative correlation with the completion duration of Test 2 in SPPB, indicating that greater gait variability might be related to better physical vitality. PC1 (Muscle-Control Reserve) and PC2 (Learning-Fatigue Response) obtained from PCA had a positive relationship with the test duration. The comprehensive index had a positive but not highly significant correlation with test scores. Conclusions: This study analyzed the correlation between the elderly's gait movement features and SPPB test performance. It innovated in data collection and analysis methods. Future research can be improved by expanding the sample size, adding more parameters, and applying deep-learning techniques.

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