Control of inter-endothelial junctions integrity by CD146 and JAMs:from molecular basis to renal inflammatory disease.-READ

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A(略)1(略)S(略)0(略)

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4(略)1(略)0(略)

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B(略)c(略)S(略)-(略)s(略)o(略),(略)s(略)a(略)l(略)e(略)n(略)p(略)i(略)

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M(略)m(略)r(略)o(略) (略)N(略)G(略)G(略)

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I(略)R(略)N(略)R(略)E(略)X(略)R(略)L(略)I(略)E(略) (略)I(略)R(略)E(略)N(略)M(略)S(略)U(略)A(略)N(略)D(略)A(略)N(略)E(略)E(略) (略)H(略)H(略)E(略)A(略)D(略)G(略)O(略)E(略)N(略) (略)A(略) (略)S(略)N(略)M(略)S(略)U(略)A(略)N(略)D(略)A(略)N(略)E(略)E(略) (略)H(略)H(略)E(略)A(略)D(略)G(略)O(略)E(略)N(略) (略)I(略)I

项目标书摘要:Su(略)mmary:The(略)l cells,w(略)he blood (略) the uniq(略)ristic to(略)e infiltr(略)ood prote(略)ls into t(略)all.This (略) mainly a(略)the coord(略)ing and c(略)ndothelia(略).Organiza(略)esive str(略)the junct(略)thelial c(略)ential fo(略)homeostas(略)equently,(略)eir archi(略)major for(略)ing their(略)scular fu(略)ce a vari(略)n disease(略)iated to (略)endotheli(略)s.The sen(略)ro-enviro(略)s,which i(略)othelial (略)diated by(略)pathways (略)toward re(略) endothel(略)e propert(略)ing that (略)lecules a(略)de-in sig(略)forms as (略)ide-out s(略)ansducers(略),CD146 an(略)y members(略)discovere(略)ant adhes(略)es of int(略)ial junct(略)t by the (略)volved in(略)ct.The pr(略)esults ge(略)the three(略)es show t(略)nd JAMs 1(略)ith Grasp(略)ed as a c(略)or for PD(略)otif and (略) as solub(略)are invol(略)control o(略)al permea(略)3/present(略)pression (略)flammator(略)These fin(略)the way o(略)ct propos(略)is to und(略) role of (略)AMs in th(略)f vascula(略),from mol(略)s to path(略)cal impli(略)order to (略) to the p(略) specific(略)he projec(略)/to chara(略) signalin(略)that regu(略)ane expre(略)luble for(略) and JAMs(略)her the c(略)pecific r(略)46 and JA(略)lar perme(略) inflamma(略)efine the(略)Ms and CD(略)l biomark(略)therapeut(略)in renal (略)y disease(略)nality of(略)t is to p(略)ntegrated(略)hich will(略)lar appro(略)imary hum(略)e endothe(略)newly and(略)veloped k(略)use model(略)es in pat(略)chronic i(略) renal di(略)elevant a(略)s.Thus,by(略)g new ele(略)e underst(略)he endoth(略)ion organ(略) function(略) will unc(略)levance o(略) JAMs exp(略)inflammat(略)athology (略) propose (略)ers and/o(略)ic tools (略)tment of (略)ney disea(略)

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