项目来源

国家重点研发计划(NKRD)

项目主持人

董林林

项目受资助机构

中国中医科学院中药研究所

立项年度

2018

立项时间

未公开

项目编号

2018YFC1706302

研究期限

未知 / 未知

项目级别

国家级

受资助金额

420.00万元

学科

中医药现代化研究

学科代码

未公开

基金类别

未公开

关键词

党参 ; 种质资源 ; 新品种 ; C.pilosula ; germplasm resources ; new breeding

参与者

梁乙川

参与机构

未公开

项目标书摘要：党参种植面临种质退化、品质下降、农残超标等问题，造成药材质量下降，危害人类及环境安全，成为党参产业发展的瓶颈。抗性优质党参新品种的选育是保障其药材安全有效的有效措施。针对上述问题，通过种质资源收集，建立党参种质资源谱；基于本草基因组学技术解析党参的遗传信息，在基因组水平筛选与抗逆、优质关联的分子标记；挖掘并验证党参抗逆及调控高药效含量的关键基因，阐述其机制；结合田间生物学形状，辅助新品种的选育，建立党参分子育种体系，培育党参2个新品种，减少农药的使用量，从源头保障党参药材的安全及有效，助力党参产业的可持续发展。

Application Abstract: The planting of Codonopsis pilosula is faced with the problems of germplasm degradation,quality degradation and agricultural residues exceeding the standard,which results in the quality degradation of medicinal materials,harms human and environmental safety,and becomes the bottleneck of the development of Codonopsis pilosula industry.The breeding of new resistant and high-quality Codonopsis pilosula varieties is an effective measure to ensure the safety and effectiveness of the medicinal materials.Aiming at the above problems,the germplasm spectrum of Codonopsis codonopsis was established by collecting germplasm resources.The genetic information of Codonopsis codonopsis was analyzed based on herba genomic technology,and molecular markers associated with resistance and quality were screened at the genomic level.To explore and verify the key genes of Codonopsis pilosula for its resistance and regulation of high pharmacodynamic content and elucidate its mechanism.Combined with the biological shape of the field,assisted the breeding of new varieties,established the molecular breeding system of Codonopsis pilotiana,cultivated two new varieties,reduced the use of pesticides,ensured the safety and effectiveness of Codonopsis pilotiana from the source,and facilitated the sustainable development of Codonopsis pilotiana industry.

项目受资助省

北京市