骨骼肌减少症基于运动功能障碍的诊断标准初探
项目来源
浙(略)然(略)金
项目主持人
温(略)
项目受资助机构
浙(略)教(略)
立项年度
2(略)
立项时间
未(略)
项目编号
L(略)C(略)0(略)
项目级别
省(略)
研究期限
未(略) (略)
受资助金额
5(略)万(略)
学科
生(略)部
学科代码
未(略)
基金类别
青(略)项(略)
关键词
骨(略)减(略) (略)能(略)衰(略) (略)c(略)i(略);(略)y(略)a(略)e(略)r(略)c(略) (略)n(略)
参与者
未(略)
参与机构
未(略)
项目标书摘要:骨骼(略)肌肉萎缩、运动系统(略)的综合征,可能造成(略)受限,甚至引起老年(略)亡等严重后果。前期(略)减症诊断标准由西方(略)使用存在低估患病率(略)性不理想等问题。本(略)肌量、肌肉力量与运(略)我国老年人骨骼肌衰(略)。研究以浙(略)老(略)能x光吸收法测试了(略)法测试老年人肌肉力(略)查法测试了老年人运(略):1)老年人的骨骼(略)相关;2)采用不同(略),我国老年人骨骼肌(略)0%;3)与其他标(略)症工作组标准AWG(略).0 kg/m2 (略))和国际骨骼肌衰减(略)RASM 男性7.(略) 5.67 kg/(略)发现运动功能障碍风(略)诊断标准仍有待深入(略)
Applicati(略): Sarcope(略)riatric s(略)t is char(略)y the los(略)al muscle(略)ecrease o(略)performan(略)ancing ag(略)a could c(略)al limita(略)anding an(略)n older a(略)en lead t(略)rse conse(略)luding fa(略)es,physic(略)ty,and in(略)tality.Pr(略)ies sugge(略)he curren(略) of sarco(略)was estab(略)he West m(略)pplicable(略) populati(略)he undere(略)f prevale(略)openia as(略)or sensit(略)pecificit(略)stic indi(略)urpose of(略) was to 1(略)the assoc(略)een skele(略)mass,musc(略) and phys(略)mance of (略);2)explor(略)ostic ind(略) cutoff p(略)rcopenia (略)elderly.O(略)in Zhejia(略) was chos(略)tudy popu(略)he curren(略)ticipants(略)uscle mas(略)rength an(略)performan(略)sured by (略)p,SPPB te(略)tionnaire(略)ly.The re(略)is study (略))There ar(略)on betwee(略)lts’skele(略)mass and (略)rformance(略)alence of(略) ranged f(略)ith diffe(略)ia.;3)com(略)other sta(略)indicator(略)f points (略)a Working(略)arcopenia(略)ASM:men 7(略)men 5.4 k(略)GS(Intern(略)king Grou(略)enia)stan(略)en 7.23 k(略)5.67 kg/m(略)efficient(略)y the old(略)ith high (略)ysical li(略)urther st(略)till need(略)tigate ap(略)iagnostic(略)of sarcop(略)inese pop(略)
项目受资助省
浙(略)
1.骨骼肌衰减症基于运动功能障碍的诊断标准的初步研究(Preliminary study of diagnostic standards for sarcopenia in terms of risk of physical limitations)
- 关键词:
- 骨骼肌衰减症、运动功能、衰老、Sarcopeina、physical performance、aging
- 温煦;
- 《浙江大学;》
- 2015年
- 报告
骨骼肌衰减症是增龄过程中由肌肉萎缩、运动系统功能下降引起一系列症状的综合征,可能造成老年人站立、步行等活动受限,甚至引起老年人跌倒、骨折、残疾、死亡等严重后果。前期研究发现现行的骨骼肌衰减症诊断标准由西方国家引入,在中国人群中使用存在低估患病率、诊断指标敏感性和特异性不理想等问题。本研究旨在研究老年人骨骼肌量、肌肉力量与运动功能的关系,初步探索我国老年人骨骼肌衰减症的诊断指标和临界值。研究以浙江省老年人为研究对象,采用双能x光吸收法测试了老年人骨骼肌含量、握力法测试老年人肌肉力量、SPPB法和问卷调查法测试了老年人运动功能等指标。研究发现:1)老年人的骨骼肌含量与其运动功能存在相关;2)采用不同现行的骨骼肌衰减症标准,我国老年人骨骼肌衰减症的患病率在0-10%;3)与其他标准相比,亚洲骨骼肌衰减症工作组标准AWGS(RASM 男性 7.0 kg/m2 女性5.4 kg/m2)和国际骨骼肌衰减症工作组标准IWGS(RASM 男性7.23 kg/m2 女性 5.67 kg/m2)标准的确更有助于发现运动功能障碍风险。我国的骨骼肌衰见症诊断标准仍有待深入研究。 Sarcopenia is a geriatric syndrome that is characterized by the loss of skeletal muscle mass and decrease of physical performance with advancing age.Sarcopenia could cause physical limitations of standing and walking in older adult,and even lead to some adverse consequences including falls,fractures,physical disability,and increased mortality.Previous studies suggested that the current criterion of sarcopenia that was established in the West may be not applicable in Chinese population due to the underestimation of prevalence of sarcopenia as well as poor sensitivity and specificity of diagnostic indictors.The purpose of this study was to 1)determine the association between skeletal muscle mass,muscle strength and physical performance of older adult;2)explore the diagnostic indicators and cutoff points of sarcopenia in Chinese elderly.Older adult in Zhejiang province was chosen as the study population in the current study.Participants’skeletal muscle mass,muscle strength and physical performance were measured by DEX,handgrip,SPPB test and questionnaire respectively.The results of this study show that:1)There are association between older adults’skeletal muscle mass and physical performance;2)The prevalence of sarcopenia ranged from 0%-10%with different criteria.;3)compared with other standards,the indicators and cutoff points in AWGS(Asia Working Group on Sarcopenia)standard(RASM:men 7.0 kg/m2;women 5.4 kg/m2)and IWGS(International Working Group on Sarcopenia)standard(RASM:men 7.23 kg/m2;women 5.67 kg/m2)are more efficient to classify the older adults with high risk for physical limitations.Further studies are still needed to investigate appropriate diagnostic criterion of sarcopenia for Chinese population.
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