Photoacids and bases as responsive elements in block copolymer nanostructures for uptake and transport(A03)

项目来源

德国科学基金(DFG)

项目主持人

Benjamin Dietzek-Ivansic

项目受资助机构

Friedrich-Schiller-Universität Jena;

立项年度

2017

立项时间

未公开

项目编号

387318883

项目级别

国家级

研究期限

未知 / 未知

受资助金额

未知

学科

Preparatory and Physical Chemistry of Polymers

学科代码

未公开

基金类别

Collaborative Research Centres

关键词

未公开

参与者

Felix H.Schacher;Klaus D.Jandt

参与机构

未公开

项目标书摘要:The project addresses triggered drug release by red/NIR light from new polymeric nanocontainers.To this end we research different block copolymer concepts to couple triplet-triplet annihilation upconversion to chemical reactivity of photoacids and photobases leading to drug release.Furthermore,based on polymers developed during the first funding period we will study the light-mediated formation and dissociation of interpolyelectrolyte complexes(IPECs)as another tool for drug transport and temporally controlled release.

Application Abstract: The project addresses triggered drug release by red/NIR light from new polymeric nanocontainers.To this end we research different block copolymer concepts to couple triplet-triplet annihilation upconversion to chemical reactivity of photoacids and photobases leading to drug release.Furthermore,based on polymers developed during the first funding period we will study the light-mediated formation and dissociation of interpolyelectrolyte complexes(IPECs)as another tool for drug transport and temporally controlled release.

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