分子影像指导的食管鳞癌根治性放化疗后失败模式及挽救性治疗的探寻

项目来源

山(略)技(略)

项目主持人

韩(略)

项目受资助机构

山(略)瘤(略)究(略)

立项年度

2(略)

立项时间

未(略)

项目编号

2(略)GSF118017

项目级别

省(略)

研究期限

未(略) (略)

受资助金额

2(略)0(略)

学科

人(略)康

学科代码

未(略)

基金类别

重(略)计(略)

关键词

食(略) (略)疗(略)化(略) (略)式(略)分(略) (略)救(略) (略)s(略)a(略)l(略)u(略)u(略)e(略)c(略)i(略)a(略)r(略)o(略)r(略) (略)h(略)t(略)a(略);(略)i(略)e(略)d(略) (略)e(略)a(略)m(略)n(略) (略)v(略) (略)r(略)

参与者

未(略)

参与机构

未(略)

项目标书摘要:食管(略)疗模式下,根治性放(略)少为临床肿瘤学家所(略)示踪剂FDG进行显(略)性放化疗后失败病灶(略)施。本研究于201(略)12月累计入组患者(略)按照既定治疗方案完(略)例纳入本研究分析。(略)PET-CT检查,(略)后失败的食管鳞癌病(略)并测量最大标准摄取(略)谢体积(MTV),(略)建失败模式分布图,(略)淋巴结转移部位、远(略)注。根据患者的体力(略)行实施包括手术、再(略)疗及最佳支持治疗的(略)lan-Meier(略)rank法检验,分(略)对患者生存率的影响(略)%,根治性放化疗后(略)救性治疗包括手术2(略)单纯放疗4例、化疗(略);放射性皮肤反应1(略)、4级皮肤反应发生(略),2级4例,无3、(略)未观察到放射性心脏(略)反应率46.67%(略),2年OS为23.(略)筛选的失败患者进行(略)好的2年OS,而能(略)纯放疗或单纯化疗者(略)者预后最差。分组分(略)MTV较低的一组生(略)论的得出同时受到样(略)在偏倚。本研究的结(略)的证实及补充,同时(略)max、MTV进行(略)

Applicati(略): The spe(略)of failur(略)ical chem(略)py is les(略)clinical (略) under th(略) imaging (略) esophage(略) cell car(略)rder to g(略)plementat(略)cal chemo(略)y,the mol(略)er FDG wa(略)uantitati(略)e the fai(略)phageal s(略)l carcino(略)dical rad(略)nd chemot(略)ods:from (略) December(略)tal of 39(略)ere enrol(略) study,ex(略) various (略)patients (略)ed in the(略)yse,enven(略) FDG PET-(略)ion on th(略)accurate (略) of radic(略)rapy and (略)y after f(略)sophageal(略)ell carci(略) location(略)the numbe(略)s and to (略) maximum (略)take valu(略)olume(MTV(略) to the m(略)atomic lo(略)sophageal(略)struction(略) mode dis(略)he local (略)ation lym(略)astasis a(略)metastasi(略) site,det(略).Accordin(略)al condit(略)ge of dis(略)e treatme(略)g operati(略)herapy,ra(略)chemother(略)t support(略)nt were c(略)The Kapla(略)hod was u(略)ulate the(略)ate and t(略) test.The(略)SUVmax an(略)e surviva(略)atients w(略).Results:(略)up rate w(略)ases,2 ca(略)hemothera(略)ses,4 cas(略)iotherapy(略)herapy in(略)d best su(略)erapy as (略)rapy in p(略)h esophag(略)s cell ca(略)er radica(略)apy and c(略) after fa(略)ding surg(略)tive skin(略)rade 1 8 (略) 2 in 5 c(略)rade 4,gr(略)reaction;(略)radiation(略)ng injury(略) grade 2,(略)ithout th(略)e of radi(略)ed lung i(略)dioactivi(略)rved in h(略)inal cord(略)ients.The(略)ate was 4(略)edian sur(略)was 8 mon(略) 2 year O(略)%.Conclus(略)udy found(略) screenin(略)nderwent (略)gery achi(略)s OS,and (略)y is supe(略)iotherapy(略)erapy,the(略)of patien(略)g best su(略)re is the(略)p analysi(略)at a lowe(略)SUVmax an(略)onger sur(略)the highe(略)usion is (略)by the sm(略)e size,an(略) be bias.(略)ions of t(略)eed to be(略)n the con(略)nd supple(略)e samples(略)e time,fu(略)ification(略)an be car(略)cording t(略) SUVmax a(略)

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