Notchandp53-howdotheycontributetolungcancertumorigenesis?

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德(略)基(略)F(略)

项目主持人

G(略)S(略)i(略)r(略)-(略)i(略)

项目受资助机构

U(略)l(略)k(略)n(略)i(略)f(略)n(略)e(略)i(略)I

项目编号

2(略)3(略)4

立项年度

2(略)

立项时间

未(略)

研究期限

未(略) (略)

项目级别

国(略)

受资助金额

0(略)欧(略)

学科

H(略)t(略)g(略)n(略)o(略)

学科代码

未(略)

基金类别

R(略)a(略)F(略)o(略)i(略)

关键词

未(略)

参与者

K(略)-(略)W(略)

参与机构

未(略)

项目标书摘要:Ca(略)adingcaus(略)ldwideand(略)reproject(略)ther,resu(略)timated12(略)hsin2030.(略)tamountof(略)-relatedd(略)ibutablet(略).Although(略)hnologies(略)generatio(略)permitade(略)intotheun(略)eticlesio(略)uscells,w(略)oundersta(略)ingaberra(略)networks.(略)genomicin(略)sentialfo(略)arthtopre(略)nttransfo(略)s,powerfu(略)lancesyst(略)amageresp(略)olved.The(略)ssorp53li(略)tofthisco(略)ingnetwor(略)entlyfoun(略)offunctio(略)nlungcanc(略)itstillre(略)rwhyp53-p(略)ngcancers(略)rivenapop(略)reatmentw(略)gingchemo(略)agents.To(略)idatethem(略)tchesofp5(略)poptosisi(略),wewillcr(略)tlydevelo(略)termouse((略)eetal.,un(略)omousemod(略)allCellan(略)ungCancer(略)earepropo(略)minehowab(略)signaling(略)ngcancert(略)s.Notonly(略)wingbodyo(略)atNotchsi(略)ichotomou(略)ndifferen(略)alsubtype(略)er,butals(略)hownthatp(略)p53-profi(略)andaberra(略)alinghave(略)lyreduced(略)es.Inthis(略)tofurther(略)theroleof(略)morsuppre(略)uethisgoa(略)eneratean(略)atableNot(略)tcanbecon(略)orallyand(略)inally,we(略)edtogaina(略)htintothe(略)tweenNotc(略)ngcancer.

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