项目来源

巴西圣保罗研究基金(FAPESP)

项目主持人

Ercy Mara Cipulo Ramos

项目受资助机构

Faculdade de Ciências e Tecnologia.Universidade Estadual Paulista.Campus de Presidente Prudente.Presidente Prudente,SP,Brazil

立项年度

2022

立项时间

未公开

项目编号

21/06065-3

项目级别

国家级

研究期限

未知 / 未知

受资助金额

未知

学科

Health Sciences

学科代码

未公开

基金类别

Regular Research Grants

关键词

Neoplasias de cabeça e pescoço ; Treinamento físico combinado ; Composição corporal ; Qualidade de vida ; Força muscular ; Neoplasias pulmonares ; Fisioterapia respiratória ;

参与者

Fabiano Francisco de Lima；Isis Grigoletto Silva；Luis Alberto Gobbo；Vinícius Cavalheri de Oliveira

参与机构

未公开

项目标书摘要：Lung and head and neck cancers are known for its high prevalence and mortality rates.Chemotherapy and/or radiotherapy are usually recommended as the main treatment(s)for this disease;however,they can negatively impact both the physical and mental status of patients.Hence,it is reasonable to consider resistance and/or aerobic exercise training to prevent the impact of the disease and its treatment(s).Further,several factor prevent patients to attend outpatient exercise training programs and,therefore,a semi-supervised home-based exercise training program could be well accepted.Aims:To investigate in people with primary lung cancer or head and/or neck cancer,the protective effect of a semi-supervised home-based exercise training(resistance and aerobic)on physical performance,biological and mental outcomes,prevention of the reduction of the initial oncological treatment dose prescribed,number of hospitalizations in three,six and nine months and on 12-month survival.Methods:Participants with primary lung or head and/or neck cancer will be randomized into:TG:Training Group and CG:Control Group.The TG will undergo semi-supervised home-based aerobic and resistance exercise training during their usual oncology treatment(radiotherapy and/or chemotherapy)period.This intervention will start one week before the usual oncology treatment,will be performed throughout the duration of the treatment,and will continue for two weeks after treatment completion.The CG will undergo usual oncology treatment.Assessment will take place two weeks before the beginning of the usual oncology treatment and two weeks after treatment completion.Measures will be collected of:physical outcomes(muscle strength,functional capacity and physical activity level),biological parameters(body composition)and mental(symptoms of anxiety and depression,quality of life and symptoms related to the disease and treatment).We will also assess satisfaction with the intervention,hospitalization in 3,6 and 9 months,survival in 12 months and any change in dose of oncological treatment.Statistical Analysis:The data normality will be verified by the Kolmogorov-Smirnov test.For intra and intergroup analyzes of the basal and final moments of GT and CG,t Student test or Mann-Whitney test will be used,according to the normality of data.(AU)

Application Abstract: Lung and head and neck cancers are known for its high prevalence and mortality rates.Chemotherapy and/or radiotherapy are usually recommended as the main treatment(s)for this disease;however,they can negatively impact both the physical and mental status of patients.Hence,it is reasonable to consider resistance and/or aerobic exercise training to prevent the impact of the disease and its treatment(s).Further,several factor prevent patients to attend outpatient exercise training programs and,therefore,a semi-supervised home-based exercise training program could be well accepted.Aims:To investigate in people with primary lung cancer or head and/or neck cancer,the protective effect of a semi-supervised home-based exercise training(resistance and aerobic)on physical performance,biological and mental outcomes,prevention of the reduction of the initial oncological treatment dose prescribed,number of hospitalizations in three,six and nine months and on 12-month survival.Methods:Participants with primary lung or head and/or neck cancer will be randomized into:TG:Training Group and CG:Control Group.The TG will undergo semi-supervised home-based aerobic and resistance exercise training during their usual oncology treatment(radiotherapy and/or chemotherapy)period.This intervention will start one week before the usual oncology treatment,will be performed throughout the duration of the treatment,and will continue for two weeks after treatment completion.The CG will undergo usual oncology treatment.Assessment will take place two weeks before the beginning of the usual oncology treatment and two weeks after treatment completion.Measures will be collected of:physical outcomes(muscle strength,functional capacity and physical activity level),biological parameters(body composition)and mental(symptoms of anxiety and depression,quality of life and symptoms related to the disease and treatment).We will also assess satisfaction with the intervention,hospitalization in 3,6 and 9 months,survival in 12 months and any change in dose of oncological treatment.Statistical Analysis:The data normality will be verified by the Kolmogorov-Smirnov test.For intra and intergroup analyzes of the basal and final moments of GT and CG,t Student test or Mann-Whitney test will be used,according to the normality of data.(AU)